Expression of mucin 3 and mucin 5AC in arthritic synovial tissue
نویسندگان
چکیده
منابع مشابه
Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.
OBJECTIVE Rheumatoid arthritis (RA) is a chronic inflammatory disease that is characterized by hypertrophy of the synovial tissue, leukocyte infiltration, angiogenesis, and ultimately joint destruction. Mucins (MUCs) are a family of heavily glycosylated proteins that protect epithelial membranes and are used as ligands for cell adhesion. MUC gene expression has been found to be altered in many ...
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Synovial mucin, the characteristic component of synovial fluid, was first isolated in 1846 by Frerichs (1846), who precipitated it from joint fluid by addition of. acetic acid. Its high viscosity and peculiar chemical composition made it a subject of much interest. Frerichs realized that it was a complex of protein and carbohydrate components, but little -additional information was added until ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2007
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.23174